Primary bone sarcomas are rare cancers that arise directly from the bone and represent 0.2% of all tumors. A majority of bone cancers arise sporadically without any known cause, however, some bone sarcomas are associated with a pre-existing condition such as Paget disease, radiation injury, genetic mutation, bone infarction, chronic infection and pre-existing benign tumors. The most common location is around the knee and the pelvis, but any bone can be involved.
Primary bone sarcomas have a bimodal age distribution, having a higher incidence in young adults and elderly patients. The most common symptoms associated with a bone sarcoma include progressive pain, swelling, pathologic fracture and secondary finding. In particular, non-mechanical or non-weight bearing pain, specifically pain at night while at rest, is a common complaint with primary bone sarcomas.
At the Parkview Cancer Institute, we have a dedicated Sarcoma Care Team including radiation oncology, medical oncology, interventional radiology, pathology, plastic surgery, nurse navigation, genetics, nutrition, spiritual support, and financial support, led by our orthopedic oncology team.